This species name is derived from the Latin 'flavus' meaning yellow and 'macula' meaning with spots, referring to the pattern found on the backs of many juveniles.
L. flavomaculatus adults in the gray-brown phase may easily be confused with adult L. vermiculatus, which have a nearly identical adult color phase. The most reliable means of differentiating between the two species is to compare the toe webbing, which is more extensive in L. vermiculatus, with the inner web reaching the disks of the first three digits (Text from Harper et al., 2010).
The following is the original description from Günther (1864):
Tympanum scarcely conspicuous; tougue deeply notched behind; snout short, broad; upper parts quite smooth, dark violet, with rounded yellow spots irregularly disposed; one of these spots on each elbow and heel; the hind margin of the fore arm and of the tarsus yellow. Upper lip yellow, lower parts whitish.
Two color phases exist. Juveniles and some adult males are bright green with yellow flecks. Adult females and some adult males are gray-brown with a darker brown triangle pointing forward on the dorsum and a dark band running below the eye and covering the tympanum. Bright white patches are distinctly visible on the heels and elbows of individuals in the green phase, but are less distinct in the gray-brown phase. Adult males have pectoral glands. The snout is short and rounded. The tympanum is large and distinct, greater than ½ the diameter of the eye (Text from Harper et al., 2010).
Males measure 44 – 50 mm and 60 – 70 mm in snout-vent length (Harper et al., 2010).
L. flavomaculatus is primarily found in semideciduous forest in coastal areas, but it also occurs in lowland and montane forest up to 1600 m. It tolerates some degree of habitat degradation (Text from Harper et al., 2010).
Emerging metamorphs are commonly seen on vegetation at Amani Pond in the East Usambaras and are around 15 mm (Text from Harper et al., 2010).
Very little is known about the breeding habits of L. flavomaculatus. Males call from vegetation approximately 3-4 m above ground and from burrows on the ground. It is assumed to lay eggs in burrows near water and larvae are thought to hatch and develop in water (Harper et al., 2010).